Current treatment concepts for primary CNS lymphoma (UNI-MED Science)

By Gerald Illerhaus, Elisabeth Schorb
Primary CNS lymphomas (PCNSLs) are defined as non-Hodgkin lymphomas which, at the time of diagnosis, are located exclusively in the brain parenchyma, in the meninges and / or in the spinal cord or in the vitreoretinal area. They occur much more frequently in immunoincompetent patients than in immunocompetent patients. As a rule, it is an aggressive, diffuse large-cell B-cell lymphoma, in which the median survival time without therapy is only a few weeks to months after diagnosis.The therapeutic spectrum of PCNSL is limited by the difficulty of crossing the blood-brain barrier. If this is the case, however, the chemosensitivity is high. Due to the rarity of this tumor disease, most studies are based only on small numbers of patients with limited informative value. Nevertheless, in the last few years, it has been possible to establish promising curative therapeutic approaches that are based on induction and subsequent consolidation therapy and enable high remission rates and several years of progression-free survival.All of these aspects are taken into account in this monograph, which summarizes the current knowledge on the PCNSLs in a compact and informative way.

The book “Primary CNS Lymphomas” by Gerald Illerhaus and Elisabeth Schorb is a comprehensive guide to understanding this rare and aggressive form of non-Hodgkin lymphoma. As the title suggests, this type of lymphoma affects the central nervous system, including the brain, meninges, spinal cord, and vitreoretinal area. PCNSL occurs more often in immunoincompetent patients, and the most common type is an aggressive, diffuse large-cell B-cell lymphoma.

One of the challenges in treating PCNSL is the difficulty of crossing the blood-brain barrier. However, the chemosensitivity of PCNSL is high, and recent years have seen promising advances in curative therapeutic approaches based on induction and consolidation therapy. This book summarizes the current state of knowledge on PCNSL, presenting the latest research and treatment options in a concise and informative manner.

This monograph is a valuable resource for healthcare professionals, researchers, and patients alike. It covers a wide range of topics related to PCNSL, including diagnosis, staging, and treatment options. The book also provides insights into the unique challenges of treating PCNSL, such as managing neurological symptoms and addressing complications related to chemotherapy.

Overall, “Primary CNS Lymphomas” is a well-written and informative book that offers a comprehensive overview of PCNSL. The authors have done an excellent job of synthesizing the latest research and treatment options into an easy-to-read format. This book is a must-read for anyone involved in the care of patients with PCNSL.

If you or someone you know has been diagnosed with PCNSL, this book is an essential resource. It provides in-depth information on the disease and its treatment options, making it easier to understand what is happening and what to expect during treatment. The authors also provide practical advice on managing symptoms and coping with the emotional and psychological impact of a cancer diagnosis.

In addition to its value as a medical resource, “Primary CNS Lymphomas” is also an enjoyable read. The authors have a clear and engaging writing style that makes the book easy to follow. The content is well-organized, with clear headings and subheadings that make it easy to find specific information.

In conclusion, “Primary CNS Lymphomas” is an outstanding book that deserves a place on the bookshelf of anyone interested in understanding this rare and aggressive form of lymphoma. Whether you are a healthcare professional, researcher, or patient, this monograph provides valuable insights into the diagnosis, treatment, and management of PCNSL. Order your copy today and gain a deeper understanding of this complex and challenging disease.

Product Details

• ASIN ‏ : ‎ B09FRDD4SP
• Publisher ‏ : ‎ UNI-MED Verlag AG; 1st edition (April 8, 2021)
• Publication date ‏ : ‎ April 8, 2021
• Language ‏ : ‎ English