The Handbook of Metabolic Phenotyping

by John C. Lindon (Editor), Jeremy K. Nicholson (Editor), Elaine Holmes (Editor)

Have you ever wondered how our bodies function on a molecular level? How different factors such as nutrition, disease, and therapy affect our metabolism? If these questions pique your curiosity, then “The Handbook of Metabolic Phenotyping” is a must-read for you.

Edited by John C. Lindon, Jeremy K. Nicholson, and Elaine Holmes, “The Handbook of Metabolic Phenotyping” is the definitive work on this rapidly developing field. It provides a comprehensive exploration of metabolic phenotyping, covering the analytical chemistry techniques, statistical modeling approaches, and application areas used in the study of metabolism.

One of the key features of this handbook is its coverage of the wide array of analytical chemistry techniques employed in metabolic phenotyping. The book delves into the theoretical and practical explanations of these techniques, giving readers a deep understanding of their underlying principles and applications. Whether it’s liquid chromatography-mass spectrometry, nuclear magnetic resonance spectroscopy, or gas chromatography, this handbook covers it all.

In addition to analytical chemistry techniques, “The Handbook of Metabolic Phenotyping” also explores the diverse statistical approaches used in the field. From data preprocessing and feature selection to multivariate analysis and machine learning, the book provides a comprehensive overview of statistical modeling techniques. These statistical approaches play a crucial role in interpreting the data generated from metabolic phenotyping studies and extracting meaningful information.

The practical tips shared in this handbook are invaluable for researchers conducting their own metabolic phenotyping studies. As with any scientific endeavor, there are challenges and pitfalls to overcome. This handbook offers insights and guidance on various aspects, including study design, sample collection and preparation, data analysis, and result interpretation. By following these practical tips, researchers can increase the robustness and reproducibility of their studies.

“The Handbook of Metabolic Phenotyping” also features reviews of the various fields of activity relating to human studies. From human development to nutrition, disease, therapy, and epidemiology, the book covers a wide range of application areas. These reviews provide valuable insights into how metabolic phenotyping is currently being applied in different contexts and its potential impact on improving human health.

One of the highlights of this book is its exploration of studies that integrate various omics data sets to derive a systems biology view. Metabolomics, genomics, proteomics, and transcriptomics are all key components of systems biology, which aims to understand the complex interactions between different molecules and pathways in biological systems. By integrating these omics data sets, researchers can gain a holistic view of metabolism and uncover new insights into human biology.

“The Handbook of Metabolic Phenotyping” also addresses current issues on standardization, assay, and statistics validation, as well as data storage and sharing. These issues are crucial for ensuring the reproducibility and comparability of metabolic phenotyping studies. By establishing standardized protocols and sharing data, the scientific community can build upon each other’s work and advance the field more rapidly.

In summary, “The Handbook of Metabolic Phenotyping” is an essential resource for postgraduates and research scientists studying and furthering the field of metabolomics. Its comprehensive coverage of analytical chemistry techniques, statistical modeling approaches, and application areas provides a solid foundation for understanding metabolic phenotyping. The practical tips, reviews of different fields, and discussions on standardization and data sharing make this handbook a valuable guide for conducting high-quality metabolic phenotyping studies.

Order your copy of “The Handbook of Metabolic Phenotyping” today and delve into the fascinating world of metabolism. Gain a deeper understanding of how our bodies function at a molecular level and contribute to the advancement of this dynamic field. Whether you’re a seasoned researcher or a curious reader, this book is sure to ignite your passion for metabolic phenotyping.

Product Details

• Contains theoretical and practical explanations of all the main analytical chemistry techniques used in metabolic phenotyping
• Explores, in detail, the many diverse statistical approaches used in the field
• Offers practical tips for successfully conducting metabolic phenotyping studies
• Features reviews of all of the various fields of activity relating to human studies

• : 619 pages
• Publisher: Elsevier; 1 edition (October 19, 2018)
• Language: English
• ISBN-10: 0128122935
• ISBN-13: 978-0128122938
• Product Dimensions: 6 x 1.2 x 9 inches