By Jie Zheng, Matthew C. Trudeau

The Textbook of Ion Channels is an essential reference source for students, instructors, and researchers interested in understanding the complex world of ion channels. Written by Jie Zheng and Matthew C. Trudeau, this three-volume set explores the intricate workings of ion channels, membrane proteins that play a crucial role in controlling electrical properties, sensory responses, and overall cellular homeostasis.

Ion channels are vital for the proper functioning of neurons, cardiac cells, and other excitable tissues. They are responsible for transmitting electrical signals, allowing us to perceive sensory stimuli such as light, sound, odor, and taste, and regulating our response to physical factors like temperature and pressure. In non-excitable tissues, ion channels are instrumental in maintaining salt balance, a fundamental process for overall physiological homeostasis.

The unique location of ion channels at the cell surface membrane enables them to communicate with the external environment while also regulating intracellular homeostasis. As such, they have a profound impact on human health and are central targets for pharmaceutical interventions in the fields of mental illness, heart disease, anesthesia, pain, and other clinical applications.

The Textbook of Ion Channels covers a broad range of topics related to these membrane proteins. The three volumes provide a comprehensive introduction to fundamental concepts, technical research aspects, properties of major ion channel families, and the regulatory, physiological, and disease roles of ion channels.

Volume III – Exploring Key Aspects of Ion Channels and Their Implications

Volume III of The Textbook of Ion Channels delves into the fascinating world of ion channel regulators and their mechanisms. It explores how various factors, such as splice variants, calcium–calmodulin regulation, regulation by G proteins, and lipids, impact the function of ion channels.

The book also highlights the collaboration and interplay between different ion channels within specific physiological systems. For example, it discusses the role of ion channels in the heart, immune cells, pancreatic beta cells, and sperm and eggs. Through these case studies, readers gain insights into the importance of ion channels in healthy bodily functions.

The final section of Volume III focuses on ion channel mutations and dysfunction in specific diseases. Here, the authors examine the connection between ion channels and conditions such as epilepsy, cystic fibrosis, and pain syndromes. By understanding these disease mechanisms, researchers can potentially develop targeted treatments and interventions.

Why This Book Stands Out

The Textbook of Ion Channels distinguishes itself by providing a comprehensive and up-to-date resource for ion channel research. It covers the latest techniques used in studying ion channels, from single ion-channel measurements to animal models of ion channel diseases and human clinical trials for ion channel drugs.

The authors also present a wealth of knowledge in an accessible manner, making it suitable for readers at various levels of expertise. Whether you are a student just starting to explore ion channels or an experienced researcher seeking in-depth information, this textbook caters to your needs.

The inclusion of real-life examples and case studies enhances the understanding of complex concepts. In addition, the book provides valuable insights into the practical applications of ion channel research, paving the way for new discoveries and potential treatments.

Order Your Copy of The Textbook of Ion Channels

If you are interested in the field of ion channels or have a passion for understanding the intricate mechanisms of cellular function, The Textbook of Ion Channels is a must-read. This three-volume set offers a comprehensive guide to the world of ion channels, covering everything from fundamental concepts to cutting-edge research.

Explore the fascinating world of ion channels and discover the crucial role they play in human health and disease. Order your copy of The Textbook of Ion Channels today and embark on a journey of scientific exploration and discovery.

Product Details

• Publisher: CRC Press; 1st edition (June 28, 2023)
• Language: English
• eBook Digital: 234 pages
• ISBN-10: 0367538199
• ISBN-13: 978-0367538194