Introducing a comprehensive guide for researchers and professionals involved in drug discovery and development, Natural Products and their Bioactives in Antidiabetic Drug Discovery offers valuable insights into the potential of bioactive compounds in targeting, preventing, and managing diabetes. Written by Kanti Bhooshan Pandey, Maitree Suttajit, and Pinar Atukeren, this book bridges the gap between public research institutes and private companies working to find effective drugs to treat diabetes.

Diabetes is a global health concern that affects millions of people worldwide. The search for innovative and safe drugs to combat the complications of diabetes has become essential. Natural products derived from plants have long been used in traditional medicine to manage diabetes. The book explores recent research on new drug discovery against diabetic complications, focusing on the bioactives found in natural products.

The first part of the book provides a foundation by discussing fundamental concepts of diabetes mellitus (DM) and recent progress in drug discovery. The authors explore different druggable targets and the challenges faced in developing effective antidiabetic drugs. By presenting case studies and illustrated examples, the authors enhance reader comprehension and provide practical insights.

The second part of the book delves into bioactive compounds targeting Type-1 Diabetes. Type-1 Diabetes is characterized by the body’s inability to produce insulin. The authors investigate the use of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against Type-1 Diabetes. In this section, readers will gain valuable knowledge about the effectiveness of nutritional therapy and functional foods in managing Type-1 Diabetes.

Type-2 Diabetes, which is characterized by insulin resistance, is the focus of the third part of the book. The authors explore the mechanisms of action of different polyphenols and their potential as antidiabetic agents. They also discuss the immunomodulatory role of bioactives derived from natural products and their relevance in Type-2 Diabetes therapy.

The fourth part of the book addresses gestational diabetes, a condition that affects pregnant women. The contributors discuss the effects of natural products on the genetics of gestational diabetes, highlighting the potential of natural compounds in preventing and managing this condition.

One of the exciting aspects of this book is the exploration of nanotechnology in improving the bioavailability of bioactive compounds. By implementing nanotechnology, researchers can enhance the therapeutic potential of natural products and reduce the threshold dose required for efficacy.

Overall, Natural Products and their Bioactives in Antidiabetic Drug Discovery provides a comprehensive overview of recent research in new drug discovery against diabetic complications using bioactives from natural products. With contributions from experts in the field, this book delivers valuable insights into the potential of natural products in antidiabetic drug development.

For researchers and professionals involved in drug discovery, health care, medicinal chemistry, phytochemistry, plant science, and toxicology, this book is an essential resource. It offers a wealth of information and practical guidance for developing innovative and effective drugs to target, prevent, and manage diabetes.

Order your copy of Natural Products and their Bioactives in Antidiabetic Drug Discovery today and embark on a journey to explore the potential of natural products in combating diabetes. Whether you are a researcher, professional, or someone interested in the field, this book will provide valuable insights and deepen your understanding of antidiabetic drug discovery.