Molecular and Cellular Biology of Pathogenic Trypanosomatids (Frontiers in Parasitology)

Molecular and Cellular Biology of Pathogenic Trypanosomatids (Frontiers in Parasitology)

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Molecular and Cellular Biology of Pathogenic Trypanosomatids (Frontiers in Parasitology)

by Marcelo Santos da Silva (Author),‎ Maria Isabel N. Cano (Editor)

by Marcelo Santos da Silva (Author),‎ Maria Isabel N. Cano (Editor)

Every year millions of people living in tropical areas across the globe are affected by trypanosomatids – the parasites causing Chagas disease, African trypanosomiasis, and leishmaniasis. These diseases, classified as neglected tropical diseases by the World Health Organization, lack effective vaccines and have limited treatment options with numerous side effects. Additionally, there is a growing concern about the emergence of drug-resistant parasite strains, further complicating the management of these diseases. The significant economic burden imposed on public health systems by these diseases calls for focused research and innovative solutions.
In recent years, several research initiatives have emerged to understand the molecular and cellular biology of trypanosomatids. These initiatives aim to uncover the mechanisms of disease pathogenesis, parasite-host interactions, molecular mechanisms of drug resistance, and new therapeutic strategies. The book “Frontiers in Parasitology: Trypanosomatid Molecular and Cellular Biology” presents the latest discoveries in this field and addresses crucial aspects of trypanosomatid biology.

Understanding Trypanosomatid Diseases

The book begins by providing an overview of the diseases caused by trypanosomatids, namely Chagas disease, African trypanosomiasis, and leishmaniasis. These diseases primarily affect individuals living in tropical regions and are considered neglected tropical diseases due to the lack of attention and resources dedicated to their control. The impact of these diseases on public health is immense, with millions of people affected each year.
The lack of effective vaccines and the limited treatment options for these diseases highlight the urgent need for research and development in the field of trypanosomatid biology. The book highlights the challenges faced in tackling these diseases and showcases the significant progress made in recent years.

New Discoveries in Trypanosomatid Molecular and Cellular Biology

The book delves into various aspects of trypanosomatid molecular and cellular biology. It covers topics such as cell organization during development, genome organization and maintenance, control of gene expression, nuclear and kinetoplast DNA replication, and mechanisms of DNA damage repair. These fundamental aspects of parasite biology are essential for understanding the pathogenesis of trypanosomatid diseases.
The book also explores the virulence factors used by trypanosomatids to evade the host immune response, shedding light on the mechanisms employed by these parasites to establish infection and persist within their host. Understanding these mechanisms is crucial for the development of novel therapeutics and vaccines.
In addition, the book showcases new methods for molecular diagnosis, which play a vital role in the early detection and management of trypanosomatid diseases. These diagnostic tools enable healthcare providers to identify infected individuals promptly, leading to timely treatment and prevention of disease spread.

Implications and Applications

This comprehensive monograph will benefit a wide range of readers, including undergraduates (premedical and biologists), graduates (masters and Ph.D. students), and researchers in the field of parasitology. The book not only provides an in-depth understanding of trypanosomatid molecular and cellular biology but also highlights the significance of these findings in developing new anti-parasite treatments and eradication strategies.
Readers interested in parasitology research and related fields will find the book to be an invaluable resource. It offers a comprehensive overview of the latest discoveries in the field and highlights the urgent need for further research and innovation.

Promoting the Book

Order your copy of “Frontiers in Parasitology: Trypanosomatid Molecular and Cellular Biology” today and dive into the fascinating world of trypanosomatid research. Gain insights into the intricate molecular mechanisms used by these parasites and explore potential avenues for novel therapeutic approaches.
With its 613 pages of in-depth exploration and well-organized content, this book is an essential addition to the collection of anyone interested in parasitology and tropical diseases. Stay up-to-date with the latest advancements in trypanosomatid research and contribute to the global efforts in combatting these neglected tropical diseases.

Product Details

  • Series: Frontiers in Parasitology (Book 1)
  • : 613 pages
  • Publisher: Bentham Science Publishers (February 16, 2017)
  • Language: English
  • ISBN-10: 1681084066
  • ISBN-13: 978-1681084060
  • Product Dimensions: 7 x 1.4 x 10 inches

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