by Jaishree Paul (Author),‎ Rohini Muthuswami (Author)

With the rapid advancements in the field of molecular biology, scientists have discovered the immense potential of miRNA as a tool for therapeutic interventions. miRNAs are small non-coding RNA molecules that play a crucial role in gene expression regulation. They can act as either oncogenes or tumor suppressors, making them a promising target for cancer treatment. Additionally, miRNAs have been implicated in various other diseases, including cardiovascular diseases, neurological disorders, and viral infections. Understanding the mechanisms underlying miRNA biology is key to developing effective therapeutic strategies.

In “MicroRNA Therapeutics: A Comprehensive Guide,” the authors provide a comprehensive overview of the field, starting with an introduction to miRNA biology and functions. They then explore the various methods used for miRNA detection and analysis, as well as the challenges and limitations associated with miRNA delivery. The book also discusses the different approaches taken for miRNA therapeutic development, including the use of miRNA mimics, antisense oligonucleotides, and small molecule inhibitors. The authors highlight the progress made in preclinical and clinical studies and present case studies of miRNA-based therapies currently in development.

One of the key strengths of this book is its emphasis on the challenges and hurdles that need to be overcome for miRNA-based therapies to become a reality. The authors discuss the issues related to miRNA target identification, off-target effects, and delivery strategies. They also address the concerns regarding miRNA stability and immunogenicity. By addressing these challenges, the authors provide insights into the future directions in miRNA therapeutics and the potential impact they can have on human health.

Readers with a basic understanding of molecular biology and genetics will find this book to be an invaluable resource. The authors present the information in a clear and concise manner, making it accessible to both researchers and clinicians interested in miRNA therapeutics. The inclusion of figures and illustrations further aids the understanding of complex concepts.

In conclusion, “MicroRNA Therapeutics: A Comprehensive Guide” is a must-read for anyone interested in the exciting field of miRNA therapeutics. The authors provide a detailed overview of miRNA biology, discuss the progress made in the development of miRNA-based therapies, and highlight the challenges that need to be addressed. This book is a valuable resource for researchers, clinicians, and students alike, who are looking to expand their knowledge and stay up-to-date with the latest advancements in the field of miRNA therapeutics.

Product Details

• eBook Digital: 216 pages
• Publisher: CRC Press; 1 edition (March 12, 2018)
• Language: English
• ISBN-10: 1138054836
• ISBN-13: 978-1138054837

Order your copy of “MicroRNA Therapeutics: A Comprehensive Guide” today and delve into the fascinating world of miRNA research. Discover the potential of miRNA as a therapeutic agent and gain insights into the challenges and future directions in miRNA-based therapies. This book is a valuable resource for anyone interested in molecular biology, genetics, and therapeutic medicine.