By Said M. Afify, Masaharu Seno
This comprehensive guide delves into the intriguing world of stem cells and cancer stem cell generation within the context of the inflammatory microenvironment. Authors Said M. Afify and Masaharu Seno present a step-by-step approach, equipping researchers with the necessary techniques and manuals to study stem cells and cancer stem cells in the field of cancer research.

One of the revolutionary breakthroughs in recent years is the development of induced pluripotent stem cells, which has paved the way for studying cancer initiation without the need for mutations or foreign genes. Afify and Seno’s book focuses on the research conducted by their group, who were the first to successfully generate cancer stem cells from stem cells in the presence of inflammatory conditions. With their extensive expertise, the authors are able to share invaluable insights and practical methodologies.

The book comprises twenty insightful chapters, each covering a different facet of stem cells and cancer stem cell generation. Beginning with generating pluripotent stem cells, the authors provide instructions on converting normal stem cells into cancer stem cells. They also explore methods for enriching, isolating, and evaluating cancer stem cells. Additionally, the book delves into the characterization of cancer stem cells and potential therapeutic approaches.

Researchers will greatly benefit from the user-friendly protocols outlined in this book, which facilitate in-depth study of cancer stem cells. The authors adeptly employ illustrations to enhance readers’ understanding of how the method of cancer stem cell generation can be effectively employed as an essential tool for assessing the carcinogenic potential of various non-mutagenic compounds.

This book assumes its place as an invaluable resource for graduate students, researchers, technicians, and physicians working in academic, hospital, and pharmaceutical settings. Its comprehensive coverage and practical applications make it an essential addition to any scientific library.

An Introduction to Stem Cells and Cancer Stem Cell Generation

Stem cells are undifferentiated cells with the remarkable ability to self-renew and differentiate into various specialized cell types. These cells play a crucial role in the development and regeneration of tissues and organs. In recent years, stem cells have gained significant attention in the field of cancer research due to their potential involvement in tumor initiation, growth, and metastasis.

Cancer stem cells (CSCs) are a subpopulation of cells within tumors that possess stem-like properties. These properties include self-renewal and the ability to differentiate into the diverse cell types that constitute the tumor. CSCs are thought to be responsible for tumor recurrence, therapeutic resistance, and metastasis, making them a fascinating subject of study.

Induced pluripotent stem cells (iPSCs) represent a groundbreaking technology that allows the reprogramming of differentiated cells, such as skin cells or blood cells, back into an embryonic-like state. This remarkable technique eliminates the ethical concerns associated with using embryonic stem cells and enables the generation of patient-specific stem cells. iPSCs hold immense potential for regenerative medicine, disease modeling, and drug discovery.

Key Features of the Book

One of the highlights of this book is its emphasis on stem cell and cancer stem cell generation within the inflammatory microenvironment. The authors provide detailed insights into the specific conditions required to induce the transformation of normal stem cells into cancer stem cells.

The step-by-step protocols outlined in the book make it exceptionally user-friendly for researchers. The authors have meticulously designed and optimized these protocols to ensure reproducibility and reliability, allowing researchers to confidently undertake their experiments.

The book also delves into the evaluation and characterization of cancer stem cells. It provides comprehensive methodologies to assess the unique properties and behavior of these elusive cells. Furthermore, the authors explore possible therapeutic strategies to target and eliminate cancer stem cells, potentially revolutionizing cancer treatment approaches.

With its extensive coverage and practical applications, this book serves as an invaluable resource for researchers seeking to deepen their understanding of stem cells and cancer stem cells. It bridges the knowledge gap by providing a detailed account of the cutting-edge research conducted by the authors’ group, offering a wealth of invaluable information and expertise.

Why You Should Order This Book

This book offers an unprecedented opportunity to delve into the captivating world of stem cells and cancer stem cell generation. Researchers and individuals interested in the field of cancer research will find this book instrumental in expanding their knowledge and skill set.

The step-by-step techniques, protocols, and manuals provided in this book are essential tools for conducting thorough and accurate research. Researchers can confidently embark on their experiments knowing they have access to a reliable resource that covers all aspects of stem cell and cancer stem cell generation.

By mastering the techniques outlined in this book, researchers can contribute to the advancement of cancer research and potentially pave the way for groundbreaking therapeutic interventions. The understanding of CSCs holds immense promise in developing targeted therapies that can effectively eliminate these cancer-driving cells.

If you are a graduate student, researcher, technician, or physician working in the fields of academia, hospitals, or pharmaceuticals, this book is an indispensable addition to your library. Its comprehensive coverage, easy-to-follow protocols, and practical applications make it an invaluable resource for anyone seeking to deepen their understanding of stem cells and cancer stem cells.

Don’t miss out on the opportunity to acquire this trailblazing book. Order your copy today and unlock the door to a world of knowledge and possibilities within the realm of stem cells and cancer stem cell generation.

Product Details

• Publisher ‏ : ‎ Springer; 1st ed. 2023 edition (May 27, 2023)
• Language ‏ : ‎ English
• Hardcover ‏ : ‎ 260 pages
• ISBN-10 ‏ : ‎ 9819913306
• ISBN-13 ‏ : ‎ 978-9819913305