Lipoprotein(a) (Contemporary Cardiology) 

By Karam Kostner, Gerhard M. Kostner, Peter P. Toth

“Lipoprotein(a): An Essential Resource for Cardiovascular Health” is a comprehensive and authoritative book authored by Karam Kostner, Gerhard M. Kostner, and Peter P. Toth. This book provides an in-depth analysis of Lipoprotein(a) [Lp(a)], a unique lipoprotein that has emerged as an independent risk factor for cardiovascular vascular disease. The book covers all aspects of Lp(a) in great detail, ranging from pathophysiology to metabolism, thereby making it an invaluable resource for physicians, medical students, residents, fellows, and allied health professionals in lipidology, cardiology, endocrinology, pharmacotherapy, and health promotion and disease prevention.

The book highlights the importance of Lp(a) as a risk factor for cardiovascular disease. Several case-control studies, epigenetic studies, and mendelian randomization studies indicate that people with elevated Lp(a) have a two-fold to four-fold increased risk of cardiovascular events compared to people with low Lp(a) levels. However, despite this risk, awareness about Lp(a) among healthcare providers is still low. Even cardiologists often overlook Lp(a), in part because Lp(a) is not as well-understood as other risk factors, and treatment options are still very limited.

“Lipoprotein(a): An Essential Resource for Cardiovascular Health” is a valuable resource that fills this gap in awareness and understanding of Lp(a). Written in easy-to-understand language, this book provides a contemporary view of the roles Lp(a) plays in cardiovascular disease. In addition, it covers the clinical implications of elevated Lp(a) and current and future therapeutic options.

The book begins with an overview of the various lipoprotein classes and their functions, providing a foundation for the reader to understand the unique qualities of Lp(a). The authors then delve deep into the pathophysiology of Lp(a), including its structure, metabolism, and genetics. In subsequent chapters, the authors explore the association of Lp(a) with various cardiovascular diseases, including coronary artery disease, peripheral vascular disease, cerebrovascular disease, valvular heart disease, and renal disease. They also discuss the latest advancements in diagnostic techniques and screening methods to measure Lp(a) levels accurately.

One of the most important sections of the book deals with current and future therapeutic options for reducing Lp(a) levels. While there are no FDA-approved therapies specifically targeting Lp(a) at present, several drugs, such as niacin, PCSK9 inhibitors, antisense oligonucleotides, and gene therapy, are in various stages of development. The authors provide a comprehensive review of these options, highlighting their benefits and drawbacks, and offer practical advice on how to manage patients with elevated Lp(a) levels.

In conclusion, “Lipoprotein(a): An Essential Resource for Cardiovascular Health” is an essential resource for anyone seeking to deepen their understanding of Lp(a) and its role in cardiovascular disease. The book’s comprehensive coverage, practical advice, and easy-to-understand language make it an excellent guide for both novice and advanced practitioners. With cardiovascular disease still accounting for more than 17 million deaths worldwide each year, the book provides a timely reminder of the importance of detecting and managing Lp(a) levels to improve cardiovascular outcomes. I strongly recommend this book to anyone who wishes to enhance their clinical skills and make a positive impact on the health of their patients.

To order this book, please visit the publisher’s website or any other online retailer. With its engaging style, insightful analysis, and practical advice, “Lipoprotein(a): An Essential Resource for Cardiovascular Health” is a must-read for anyone interested in improving their understanding of Lp(a) and improving cardiovascular health.

Product Details

• Publisher ‏ : ‎ Humana; 1st ed. 2023 edition (March 4, 2023)
• Language ‏ : ‎ English
• Hardcover ‏ : ‎ 460 pages
• ISBN-10 ‏ : ‎ 3031245741
• ISBN-13 ‏ : ‎ 978-3031245749