Huntington Disease, Volume 144 (Handbook of Clinical Neurology)

by Andrew S. Feigin (Editor), Karen E. Anderson (Editor)

Huntington’s disease, also known as Huntington’s chorea, is a genetic disorder that causes the degeneration of nerve cells in the brain. It is a progressive disease, which means that it worsens over time and affects a person’s movement, behavior, and cognitive abilities. There is no cure for the illness, but research into the disease has produced much understanding of its character and treatments. The Handbook of Clinical Neurology series has published the latest research on the disease in a book edited by Andrew S. Feigin and Karen E. Anderson called Huntington Disease. The book is an excellent summary of the most recent findings on the disease, providing both cutting edge coverage for clinical/research specialists looking to expand their knowledge base of Huntington disease information, as well as solid groundwork for advanced students from various backgrounds (neurology, psychiatry, neuropsychology, genetics).

The book is an essential resource for the non-neurologist, including necessary background for understanding the disease before making a more detailed study proposal. It provides an interdisciplinary approach that can be applied in everyday clinic and research efforts by covering both basic science and clinical aspects of the disease, as well as treatment, experimental therapeutics, and biomarkers. The book features chapters edited by leaders in the field from around the world; hence, it provides the broadest expert coverage available.

The devastating nature of Huntington’s disease is well appreciated throughout the neuroscience, neurology, and psychiatric communities, and a great amount of basic and clinical research is currently taking place. However, much of that occurs in isolated research silos, and it is critical that an interdisciplinary resource be developed to provide in-depth information to enhance communication and collaboration. This volume in the Handbook of Clinical Neurology series is that resource.

One of the book’s strengths is that it addresses behavioral and cognitive symptoms, brain imaging, and family dynamics and therapeutic alliances in working with individuals affected by HD. Clinical trials are covered extensively, including design considerations for therapeutic studies. The book provides a detailed overview of HD, including genetics, pathophysiology, clinical presentation, diagnosis, and treatment.

The book is divided into two sections: the first section covers clinical aspects of HD, and the second section covers experimental therapeutics. The clinical section covers topics such as motor features of HD, psychiatric symptoms in HD, cognitive changes in HD, imaging studies, assessment, and management of HD. The second section covers topics such as animal models, drug discovery, gene therapy, and stem cell therapy.

One of the strengths of the book is that it provides diverse perspectives on topics like genetics and neurobiology. The book includes many images that will allow readers to see graphic representations of the disease and its impact on the brain of patients. The book is engagingly written, and readers who are not experts in the field can easily understand its contents.

Huntington Disease is an excellent resource for researchers, clinicians, and students who have an interest in HD. It covers all major areas of HD clinical care and research, whereas many other HD texts focus solely on neurological symptoms. It is an exceptionally thorough and comprehensive resource that is sure to become a primary reference for anyone interested in this disease.

In conclusion, Huntington Disease is an essential handbook for anyone seeking to understand this disease, including clinicians, researchers, and students. The book covers all aspects of HD, from genetics and pathophysiology to clinical presentation, diagnosis, and treatment. It offers diverse perspectives on topics like genetics and neurobiology, and it provides many graphics that allow readers to see the disease’s impact on the brain. The book is also engagingly written and easy to understand. Therefore, if you are a specialist, expert, or student, you should definitely get your copy and advance your knowledge base on HD, as this book is something you cannot afford to miss.

Product Details

• Includes coverage of both basic science and clinical aspects of the disease, as well as treatment, experimental therapeutics, and biomarkers
• Provides an essential resource for the non-neurologist, including necessary background for understanding the disease before making a more detailed study proposal
• Provides an interdisciplinary approach that can be applied in everyday clinic and research efforts
• Features chapters edited by leaders in the field around the globe―the broadest expert coverage available

• Series: Handbook of Clinical Neurology (Book 144)
• Hardcover: 312 pages
• Publisher: Elsevier; 1 edition (November 10, 2017)
• Language: English
• ISBN-10: 0128018933
• ISBN-13: 978-0128018934
• Product Dimensions: 5.9 x 0.9 x 8.3 inches