Handbook of Neurotoxicity, 2nd Edition

By Richard M. Kostrzewa
This handbook is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. This new edition significantly expands on the information provided in the first edition, providing the latest research in neurotoxicity and highlighting the relationship between specific neurotoxins and the neurodegenerative disorders they can cause. It also includes new sections on the neurotoxicity of heavy metals, fungi, and snake venom. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.

The Handbook of Neurotoxicity by Richard M. Kostrzewa is an invaluable reference source for anyone interested in understanding how neurotoxins affect the brain and nervous system. This updated second edition provides the latest research in neurotoxicity and offers readers an expansive view of the complex relationship between neurotoxins and neurodegenerative disorders.

The book is divided into several sections, each with its own comprehensive overview of specific neurotoxins. For example, the section on heavy metals, fungi, and snake venom explores the impact of these toxins on the nervous system, their mechanisms of action, and possible prevention strategies.

Throughout the Handbook, Kostrzewa emphasizes the importance of understanding the mechanisms associated with neurotoxin use, projecting outcomes of neurotoxin treatments, and assessing neurotoxins as predictors of events leading to neurodegenerative disorders. The author also discusses the concept of neuroprotection and the different approaches to achieving it, including therapeutic agents and non-drug means like exercise.

One of the most significant advantages of this book is its in-depth treatment of the topic. The author provides a detailed explanation of the structure and function of the nervous system, including the cellular and molecular mechanisms underlying neurotoxicity. This information is not only interesting but also essential for anyone working in the field of neuroscience.

Moreover, the Handbook of Neurotoxicity is written in a clear and accessible style, making it easy for researchers, neuroscientists, and laboratory investigators to understand the concepts presented. The book is well-organized, with each chapter building on the previous section, creating a logical and coherent narrative.

One of the standout features of this book is the emphasis on the relationship between specific neurotoxins and the neurodegenerative disorders they can cause. The author provides examples of these relationships, including the link between mercury and autism and the connections between lead exposure and cognitive problems. This information is particularly relevant given the growing concern over the impact of air pollution on the nervous system.

Overall, the Handbook of Neurotoxicity is an indispensable resource for anyone interested in understanding how neurotoxins affect the nervous system. It provides readers with a comprehensive overview of neurotoxicity, including the latest research, and offers practical advice on how to minimize the impact of toxins on the brain.

In conclusion, I would highly recommend this book to anyone working in the field of neuroscience, clinical research, or anyone interested in learning more about neurotoxicity. The Handbook is well-written, informative, and provides readers with a deep understanding of how neurotoxins affect the brain. It is also an excellent resource for anyone looking to order the book or video, and I am confident that readers will come away with a greater appreciation of this essential topic.

Product Details

• Publisher ‏ : ‎ Springer; 2nd ed. 2022 edition (January 3, 2023)
• Language ‏ : ‎ English
• Hardcover ‏ : ‎ 2616 pages
• ISBN-10 ‏ : ‎ 3031150791
• ISBN-13 ‏ : ‎ 978-3031150791