Genetics and Epigenetics in Breast Cancer: A Comprehensive Guide

By Madhumita Roy, Jaydip Biswas, Amitava Datta

Breast cancer is a complex disease that affects millions of women worldwide. Over the years, extensive research has been conducted to understand the genetic and epigenetic alterations that contribute to the initiation, development, and recurrence of breast cancer. In the book “Genetics and Epigenetics in Breast Cancer: A Comprehensive Guide,” authors Madhumita Roy, Jaydip Biswas, and Amitava Datta delve into the fascinating world of genetics and epigenetics to provide a comprehensive overview of the subject.

The book begins by exploring the basics of epigenetics and its role in breast cancer. It explains how epigenetic alterations, such as changes in DNA methylation patterns and histone modifications, can lead to abnormal gene expression and contribute to the development and progression of breast cancer. Readers with a background in genetics and molecular biology will find this section particularly enlightening, as it lays the foundation for the subsequent chapters.

Next, the authors discuss the genetic landscape of breast cancer. They cover various genetic mutations and alterations, such as BRCA1 and BRCA2 mutations, that are known to increase the risk of developing breast cancer. This section provides valuable insights into the genetic factors that predispose individuals to breast cancer and emphasizes the importance of genetic testing and counseling for high-risk individuals.

The book then dives into the three main epigenetic modulation mechanisms: histone modification, DNA methylation, and miRNA silencing. Each mechanism is explained in detail, along with its specific role in breast cancer. The authors highlight the potential of targeting these mechanisms for diagnostic, prognostic, and therapeutic purposes. They discuss emerging epigenetic drugs that show promise in treating breast cancer, providing hope for more effective and personalized treatment options in the future.

One of the unique aspects of this book is its focus on phytochemicals targeting epigenetic modulators in breast cancer treatment. The authors explore the potential of natural compounds found in plants, such as resveratrol and curcumin, to modulate epigenetic processes and inhibit breast cancer cell growth. This section opens up exciting possibilities for the development of novel therapeutic strategies using natural compounds.

In addition to its scientific content, “Genetics and Epigenetics in Breast Cancer: A Comprehensive Guide” is written in a clear and accessible manner. The authors explain complex concepts in a way that is easy to understand, making it suitable for both researchers and practitioners in the field of breast cancer. The book is also supported by up-to-date research and references, ensuring that readers have access to the latest advancements in the field.

Overall, “Genetics and Epigenetics in Breast Cancer: A Comprehensive Guide” is a valuable resource for anyone interested in understanding the role of genetics and epigenetics in breast cancer. Whether you are a researcher looking to expand your knowledge or a practitioner seeking new insights into breast cancer treatment, this book provides a comprehensive and up-to-date overview of the subject. Order your copy today and explore the potential of epigenetic modulators in breast cancer treatment!

Product Details

• Publisher: Springer; 1st ed. 2023 edition (May 11, 2023)
• Language: English
• Format: eBook
• Pages: 97
• ISBN-10: 9811999244
• ISBN-13: 978-9811999246