By Songlin Zhuang, Gefei Zhang, Dongxu Lei, Xinghu Yu, Mingsi Tong, Weiyang Lin, Yang Shi, Huijun Gao

This book offers readers a series of robotic methods for manipulating zebrafish larva, one of the most popular model vertebrates widely used in biomedical research and clinical applications. The authors leverage advanced control theories, image processing algorithms, and artificial intelligence to establish a robot-assisted automated or semi-automated zebrafish larva-targeted micromanipulation system for different experimental purposes. The methods presented are generic and can be translated to manipulate other types of biological objects, such as embryos or cells. Coverage includes topics that span the procedures of manipulating zebrafish larva, such as in-plane positioning, three-dimensional orientation, deformation-controllable immobilization, organ-targeted microinjection, whole-organism imaging, and high-throughput trajectory tracking of zebrafish larvae group movement.

Robotic Micromanipulation of Zebrafish Larva is a groundbreaking book that explores the intersection of robotics and biomedical research. Zebrafish larvae have become one of the most widely used model organisms due to their genetic similarity to humans and high reproductive capacity. Manipulating these larvae with precision and efficiency is essential to advancing various areas of biomedical research and clinical applications.

The authors have developed innovative robotic methods that harness advanced control theories, image processing algorithms, and artificial intelligence to create a robot-assisted micromanipulation system specifically designed for zebrafish larvae. This system allows researchers to perform automated or semi-automated manipulations of the larvae for a range of experimental purposes. The techniques presented in the book can also be adapted to manipulate other types of biological objects, such as embryos or cells.

One of the key strengths of this book is its comprehensive coverage of different procedures for manipulating zebrafish larvae. The authors provide detailed explanations and step-by-step instructions for techniques such as in-plane positioning, three-dimensional orientation, deformation-controllable immobilization, organ-targeted microinjection, whole-organism imaging, and high-throughput trajectory tracking of zebrafish larvae group movement. The book also includes illustrations, diagrams, and code snippets that enhance understanding and practical implementation.

The writing style of Robotic Micromanipulation of Zebrafish Larva is clear, concise, and accessible. The authors have made a complex subject easy to understand, making it an ideal reference for academic researchers and biomedical operators. The book is also a valuable resource for students studying robotics, control and system theories, image processing, artificial intelligence, and biomedical engineering.

From an academic perspective, this book fills a significant gap in the literature by providing a comprehensive guide to robotic micromanipulation of zebrafish larvae. It offers researchers a roadmap for implementing robotic systems in their own laboratories and expands the capabilities of zebrafish research. The techniques presented in the book have the potential to revolutionize biomedical research by enabling precise and consistent manipulation of model organisms.

Moreover, Robotic Micromanipulation of Zebrafish Larva has practical applications beyond the academic world. The research and methodology described in the book can be translated to various industries and fields requiring precise manipulation of biological objects. Industries such as pharmaceuticals, biotechnology, and medical device development can benefit from the advanced techniques presented in the book.

In conclusion, Robotic Micromanipulation of Zebrafish Larva is an invaluable resource for anyone involved in zebrafish research, robotics, or biomedical engineering. It offers a comprehensive guide to the design and implementation of robotic systems for manipulating zebrafish larvae. The book’s clear writing style, detailed explanations, and practical approach make it an essential reference for both experienced researchers and students. Order your copy today and embark on a journey at the intersection of robotics and biomedical research.

Product Details

• Publisher: Springer; 1st ed. 2023 edition (June 21, 2023)
• Language: English
• eBook Digital: 270 pages
• ISBN-10: 3031334094
• ISBN-13: 978-3031334092