Neurotoxicity of Aluminum, 2nd Edition

The book “Aluminum Neurotoxicity: From Molecular Mechanisms to Neurodegeneration” is a comprehensive review of the scientific literature and the authors’ own research on the link between aluminum exposure and cognitive impairment, specifically in relation to Alzheimer’s disease (AD). Written by Qiao Niu, this book dives into the intricate details of aluminum’s effect on the brain, discussing its levels, distribution, and its relation to the pathological features of AD.

One of the key focuses of the book is on aluminum’s presence in the brain and its region-specific and subcellular distribution. The authors examine the accumulation of aluminum in neurofibrillary tangles and amyloid beta, which are the hallmark features of AD. They explore the mechanism by which aluminum induces these pathological features, shedding light on the complex speciation chemistry of aluminum in relation to biology.

The book also delves into the role of aluminum in oxidative stress and cell death, particularly in connection with apoptosis and necroptosis. It discusses the electrophysiological variations and synaptic plasticity induced by aluminum. Additionally, the authors explore the debatable role of aluminum in AD and the interplay between aluminum and genetic susceptibility. They also highlight recent research on aluminum-induced epigenetic modifications on DNA and non-coding RNAs, and their association with neuron death and synaptic impairment.

In this second edition, the authors have updated eight chapters based on the most recent research. They have also included new content on aluminum-induced AD-like pathological features, the neurotoxic effects of aluminum and aluminum alloy nanoparticles, and the neurotoxic and neurodevelopmental toxic effects of alumina nanoparticles. This updated edition provides a comprehensive summary of aluminum neurotoxicity, incorporating the latest findings in the field.

If you are interested in understanding the current research on aluminum neurotoxicity and its potential role in cognitive impairment and AD, this book is a valuable resource. By combining extensive scientific literature review and their own research, the author provides readers with a systematic and insightful exploration of the subject matter.

Ordering the book not only allows you to access the wealth of knowledge on aluminum neurotoxicity, but it also supports the author’s research and further advancements in this field. Reading this book will give you a deeper understanding of the complex relationship between aluminum exposure and cognitive impairment, potentially inspiring further research and advancements in the prevention and treatment of neurodegenerative diseases like Alzheimer’s.

Investing in this book will prove to be a valuable addition to your collection if you are a researcher, medical professional, or someone interested in the latest scientific findings on aluminum neurotoxicity. Place your order now and embark on a journey through the fascinating world of aluminum’s impact on the brain.

Product Details

• Publisher: Springer Nature Singapore; August 3, 2023
• Language: English
• ISBN: 9789819915910
• ISBN: 9789819915927