Basic and Translational Applications of the Network Theory for Dystonia (Advances in Neurobiology, 31)

By Aasef Shaikh, Anna Sadnicka

The Network Theory of Dystonia is a newly proposed concept that suggests the disorder is related to neural networking, and the book by Aasef Shaikh and Anna Sadnicka delves into this idea in detail. Dystonia is a neurological disorder that is characterized by involuntary muscle contractions, resulting in repetitive movements or abnormal postures. The concept of dystonia as a network disorder is new and groundbreaking, and hence this book is a must-read for everyone interested in this area of research.

This book is a unique title that presents various experimental findings that support the concept of dystonia as a network disorder. The chapters have been written by experts in the field of motor systems and movement disorders, and the book aims to provide a thorough understanding of the underlying mechanisms of dystonia.

The book starts with an introduction to dystonia and the current understanding of the disorder. It discusses the various manifestations of dystonia and the lack of conclusive information regarding the brain regions that could be involved. The authors then delve into the proposed network theory of dystonia and provide evidence to support this concept. The various studies and experiments that have been conducted to validate the network theory of dystonia have been presented in a lucid and accessible manner.

One of the significant contributions of the book is that it provides an in-depth analysis of the role of dopamine in dystonia. The authors propose that dopamine could be one of the critical players in the network of the basal ganglia that controls motor behavior. The book further suggests that network-level changes in the basal ganglia could be responsible for the pathophysiology of dystonia.

Another crucial discussion in the book is the relationship between dystonia and Parkinson’s disease. The authors suggest that there may be underlying similarities between these two diseases, and the network theory of dystonia could be of immense help in designing therapies for Parkinson’s disease as well.

The book concludes by discussing the potential therapeutic implications of the network theory of dystonia. The authors suggest that understanding dystonia as a network disorder could lead to targeted interventions that could be more effective in treating the disorder. The book highlights the need for further research in this area, and it ends with a call to action for clinicians and researchers to explore this concept further.

In conclusion, The Network Theory of Dystonia is an important book that presents a new and innovative approach to understanding dystonia. The authors have presented the complex concepts in an accessible and engaging manner, making it a useful resource for both basic and clinical researchers. The book is not only informative but also thought-provoking. It promotes a feeling of curiosity and inspires readers to explore this fascinating subject even further. I would highly recommend ordering this book to anyone interested in this area of research. It is an insightful and enlightening read that is sure to leave a lasting impression.

Product Details

• Publisher ‏ : ‎ Springer; 1st ed. 2023 edition (June 21, 2023)
• Language ‏ : ‎ English
• Hardcover ‏ : ‎ 253 pages
• ISBN-10 ‏ : ‎ 3031262190
• ISBN-13 ‏ : ‎ 978-3031262197